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Detection of parvovirus B19, cytomegalovirus and enterovirus infections in cases of intrauterine fetal death by Karin Petersson; Oscar Norbeck; Magnus Westgren; Kristina Broliden is a Medicine article available to read on EtoBox.
What is Detection of parvovirus B19, cytomegalovirus and enterovirus infections in cases of intrauterine fetal death about?
Aims: Maternal infections with parvovirus B19, cytomegalovirus (CMV) and enterovirus have been associated with intrauterine fetal death (IUFD), but the incidence of these infections is not clear. This prospective study was conducted to estimate this incidence. Methods: A prospective study of 38 months was conducted on cases of IUFD referred to Huddinge University Hospital, Stockholm, Sweden. Placental biopsies, fetal blood and amniotic fluid were collected from cases of IUFD (ns52). Placental biopsies from normal pregnancies at term (ns53) were used as controls. These tissues were examined for parvovirus B19 DNA, CMV DNA and enterovirus RNA using polymerase chain reaction (PCR). Maternal viral serology was measured in 46 cases and virus isolation for enterovirus in maternal stool samples was performed in 31 cases. Results: Viral nucleic acid was recovered in at least one tissue sample from six cases of fetal death (parvovirus B19 in two cases, CMV in three and enterovirus in one), while all placental biopsies from controls were found negative. Serological signs of primary maternal infection were found in two of the cases, and virus isolation for enterovirus was negative in all samp
Who reads Detection of parvovirus B19, cytomegalovirus and enterovirus infections in cases of intrauterine fetal death?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Karin Petersson; Oscar Norbeck; Magnus Westgren; Kristina Broliden
- Publisher
- Walter de Gruyter GmbH & Co. KG; Walter de Gruyter GmbH (ISSN 0300-5577)
- Published
- 2004
- Language
- EN
- Field
- Medicine (Health Sciences)
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