Can I read Mood, Cognition and in Vivo Protein Imaging: the Emerging Nexus in Clinical Neuroscience on EtoBox?

Mood, Cognition and in Vivo Protein Imaging: the Emerging Nexus in Clinical Neuroscience by Anand Kumar; Olusola Ajilore; Vladimir Kepe; Jorge R. Barrio; Gary Small is a Medicine article available to read on EtoBox.

What is Mood, Cognition and in Vivo Protein Imaging: the Emerging Nexus in Clinical Neuroscience about?

## Abstract ## Introduction Disorders of mood and cognition overlap in the elderly and there is an emerging consensus that both groups of disorders share neurobiological substrates. ## Methods Salient peer reviewed articles focusing on late‐life depression, structural neuroimaging and recent developments in positron emission tomography based __in vivo__ protein imaging. ## Results Epidemiological and clinical evidence indicates that mood and cognition in the elderly are clinically inter‐related and common neurobiological mechanisms may underlie both groups of disorders. Degenerative, vascular and related mechanisms like genetically programmed abnormal protein deposition may provide the underlying neurobiological links between these disorders. ## Conclusions Modern neuroimaging approaches such as positron emission tomography (PET) based __in vivo__ protein binding may help further elucidate common pathophysiological mechanisms and assist in the early identification of patients at risk for developing dementia over time. These developments have important mechanistic and public health significance in the elderly. Copyright © 2007 John Wiley & Sons, Ltd.

Who reads Mood, Cognition and in Vivo Protein Imaging: the Emerging Nexus in Clinical Neuroscience?

Author

Anand Kumar; Olusola Ajilore; Vladimir Kepe; Jorge R. Barrio; Gary Small

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0885-6230)

Published

2007

Language

EN

Field

Medicine (Health Sciences)