About this Medicine article
Resolution of Persistent Oral Papillomatosis in a Dog After Treatment with a Recombinant Canine Oral Papillomavirus Vaccine by H. Kuntsi-Vaattovaara; F. J. M. Verstraete; J. T. Newsome; H. Yuan is a Medicine article available to read on EtoBox.
## Abstract This report describes a 16‐month‐old female, otherwise seemingly healthy, Siberian husky dog with severe oral papillomatosis that did not regress spontaneously and was refractory to surgical treatment over a 6‐month period. Regression of the papillomas was achieved by administering a series of experimental vaccinations starting at the time of the last surgery. The vaccine consisted of systemically administered canine oral papillomavirus major coat protein L1 that has been shown to self‐assemble into virus‐like particles. They cause a humoral response that has been shown to prevent the onset and development of papillomas. In this case, however, following unsuccessful surgical treatment, the vaccine acted therapeutically, causing the papillomas that had regrown to shrink. No side‐effects were noted.
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- Author
- H. Kuntsi-Vaattovaara; F. J. M. Verstraete; J. T. Newsome; H. Yuan
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1476-5810)
- Published
- 2003
- Language
- EN
- Field
- Medicine (Health Sciences)