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Postmastectomy lymphangiosarcoma: Ultrastructural observations by Dr. Steven G. Silverberg; Dr. Saul Kay; Dr. Leopold G. Koss is a Medicine article available to read on EtoBox.

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Two cases of lymphangiosarcomd, occurring 7 and 12 years, respectively, after radical mastectomy and radiation therapy for mammary carcinoma, have been studied with the electron microscope. Prominent vascular channels lined by highly atypical endothelial cells were present throughout both tumors. In one case, cells resembling pericytes were found in relation to many of these vessels. Numerous solid tumor cell nests seen in both cases were composed of cells characterized by a complex and well-developed smooth endoplasmic reticulum and abundant introcytoplasmic glycogen. On the basis of both optical and electron microscopic evidence, postmastectomy lymphangiosarcoma is thought to be a vascular mesenchymal tumor closely related to Kaposi's sarcoma. ## osnr.\sn;cwM\i I . ~I M I ' H A N G I O S A R C O ~~~ IS A N P iincommon malignant tumor which occurs in the upper extremity following mastectomy for mammary carcinoma. About 115 cases have been reported, of which only 3 have been studied with the electron microscope. T h e present report presents ultrastructural studies of 2 additional cases. ## C A ~E REPORIS Case 1. A 56-year-old Caucasian woman was first seen at the Medical College o

Who reads Postmastectomy lymphangiosarcoma: Ultrastructural observations?

Author

Dr. Steven G. Silverberg; Dr. Saul Kay; Dr. Leopold G. Koss

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

1971

Language

EN

ISBN

9782820270115

Field

Medicine (Health Sciences)