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MicroRNA-155 Promotes Autophagy To Eliminate Intracellular Mycobacteria by Targeting Rheb by kuyinghui is a document available to read on EtoBox.
The study investigates the role of microRNA-155 (miR-155) in promoting autophagy to eliminate intracellular Mycobacterium tuberculosis. It demonstrates that miR-155 expression is significantly increased following mycobacterial infection, which enhances autophagic responses and reduces the survival of intracellular mycobacteria by targeting Rheb, a negative regulator of autophagy. These findings provide insights into potential therapeutic targets for tuberculosis treatment by enhancing the host
- Author
- kuyinghui
- Language
- EN