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Outcomes of Salvage Surgery with Free Flap Reconstruction for Recurrent Oral and Oropharyngeal Cancer by John P. Kostrzewa; William P. Lancaster; Tim A. Iseli; Renee A. Desmond; William R. Carroll; Eben L. Rosenthal is a Medicine article available to read on EtoBox.
What is Outcomes of Salvage Surgery with Free Flap Reconstruction for Recurrent Oral and Oropharyngeal Cancer about?
## Abstract ## Objectives/Hypothesis: To evaluate outcomes of salvage surgery with free flap reconstruction for recurrent squamous cell carcinoma of the oropharynx and oral cavity with increased use of chemoradiotherapy. ## Study Design: Retrospective patient review. ## Methods: All patients undergoing salvage surgery with free flap reconstruction for oropharynx (n = 36) and oral cavity (n = 36) squamous cell carcinomas between January 2001 and January 2008 were obtained. Mean follow‐up was 14 months. Previous chemoradiotherapy was used in 40% and radiotherapy alone in 60%. ## Results: Complications were more frequent in oropharynx than oral cavity tumors (36% and 14%, respectively; __P__ = .05) requiring more secondary procedures (15 for oropharynx vs. six for oral cavity). Few patients returned to a normal diet (8%), and a majority retained an enterogastric feeding tube (56%). Median survival overall following salvage surgery was 44.8 months for oral cavity and 53.8 months for oropharynx head and neck squamous cell carcinoma. Overall estimated 1‐, 2‐, and 5‐year observed survivals were 98%, 77.2%, and 43.7%, respectively. Twelve patients had a disease‐free interval of <6 months,
Who reads Outcomes of Salvage Surgery with Free Flap Reconstruction for Recurrent Oral and Oropharyngeal Cancer?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- John P. Kostrzewa; William P. Lancaster; Tim A. Iseli; Renee A. Desmond; William R. Carroll; Eben L. Rosenthal
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); Wiley-Blackwell; Wiley (ISSN 0023-852X)
- Published
- 2009
- Language
- EN
- Field
- Medicine (Health Sciences)