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Fluconazole is an antifungal drug used to treat fungal infections. It works by inhibiting the fungal enzyme lanosterol 14-alpha-demethylase, preventing conversion of lanosterol to ergosterol and accumulation of sterols in the fungal cell membrane. Fluconazole was developed in the 1970s-1980s and approved for treatment of systemic fungal infections. Extensive literature reviews demonstrate fluconazole is effective against common Candida infections and other fungal diseases, though high minimum inhibitory con
- Author
- Shyam Yadav
- Language
- EN