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Determining an Energy Threshold for Optimal Volume Reduction of Benign Thyroid Nodules Treated by Radiofrequency Ablation by Maurilio Deandrea; Pierpaolo Trimboli; Alberto Mormile; Alice Tomasi Cont; Lisa Milan; Camille Buffet; Luca Giovanella; Paolo Piero Limone; Sylvain Poirée; Laurence Leenhardt; Gilles Russ is a Medicine article available to read on EtoBox.
What is Determining an Energy Threshold for Optimal Volume Reduction of Benign Thyroid Nodules Treated by Radiofrequency Ablation about?
## Objectives: Radiofrequency ablation (rfa) is effective in reducing the volume of benign thyroid nodules. however, what parameters can influence the response to rfa is still unclear. the present study aimed to (1) investigate which ultrasound and technical parameters are potential determinants of the volumetric reduction; (2) develop a dose-response model, and (3) analyze the effects of rfa on ultrasound features. ## Methods: In this retrospective study, three institutions treated patients with benign thyroid nodules according to the same protocol. the technical parameters were power and energy. the 1-year volume reduction ratio (vrr) was the reference standard of the response. the correlations of different parameters with vrr were analyzed and the association between several parameters and a vrr above 50% studied by uni- and multivariate analyses. the probit regression estimated the probability to achieve an effective response. ## Results: One hundred fifteen patients were enrolled. the median power was 50 w and median total delivered energy 27,531 j. at 1-year follow-up, the median vrr was 64.0% and 87 (75.7%) nodules showed a vrr above 50%. among all parameters, only baseline
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- Author
- Maurilio Deandrea; Pierpaolo Trimboli; Alberto Mormile; Alice Tomasi Cont; Lisa Milan; Camille Buffet; Luca Giovanella; Paolo Piero Limone; Sylvain Poirée; Laurence Leenhardt; Gilles Russ
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)