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Can I read N,N-Dialkylation of Acyl Hydrazides with Alcohols Catalyzed by Amidato Iridium Complexes via Borrowing Hydrogen on EtoBox?
N,N-Dialkylation of Acyl Hydrazides with Alcohols Catalyzed by Amidato Iridium Complexes via Borrowing Hydrogen by Wan-Hui Wang; Wei-Yu Shao; Jia-Yue Sang; Xu Li; Xiaoqiang Yu; Yoshinori Yamamoto; Ming Bao is a Chemistry article available to read on EtoBox.
What is N,N-Dialkylation of Acyl Hydrazides with Alcohols Catalyzed by Amidato Iridium Complexes via Borrowing Hydrogen about?
Direct N,N-dialkylation of acyl hydrazide catalyzed by a series of amidato iridium complexes bearing an electron-donating group in the ligand using methanol or ethanol as the alkyl reagent under weak base conditions (10 mol % KHCO 3 ) is described. A wide range of acyl hydrazide derivatives are converted to the corresponding N,N-dialkylated products in excellent yields (38 examples, yields of ≤96%). On the basis of the control experiments and nuclear magnetic resonance studies, a plausible mechanism was proposed. The experimental results indicate that ortho electron-donating groups on the phenyl moiety of the picolinamide ligand play a crucial role in catalytic activity.
Who reads N,N-Dialkylation of Acyl Hydrazides with Alcohols Catalyzed by Amidato Iridium Complexes via Borrowing Hydrogen?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Wan-Hui Wang; Wei-Yu Shao; Jia-Yue Sang; Xu Li; Xiaoqiang Yu; Yoshinori Yamamoto; Ming Bao
- Publisher
- American Chemical Society (ACS)
- Published
- 2023
- Language
- EN
- Field
- Chemistry (Physical Sciences)