Opening book details…
Can I read Domain-specific cognitive course in schizophrenia: Group- and individual-level changes over 10 years on EtoBox?
Domain-specific cognitive course in schizophrenia: Group- and individual-level changes over 10 years by Camilla Bärthel Flaaten; Ingrid Melle; Thomas Bjella; Magnus Johan Engen; Gina Åsbø; Kristin Fjelnseth Wold; Line Widing; Erlend Gardsjord; Linn-Sofie Sæther; Merete Glenne Øie; Siv Hege Lyngstad; Beathe Haatveit; Carmen Simonsen; Torill Ueland is a Medicine article available to read on EtoBox.
What is Domain-specific cognitive course in schizophrenia: Group- and individual-level changes over 10 years about?
Cognitive impairments in schizophrenia are well-documented, present across several cognitive domains and found to be relatively stable over time. However, there is a high degree of heterogeneity and indications of domain-specific developmental courses. The present study investigated the 10-year cognitive course in participants with first-episode schizophrenia (FES) and healthy controls on eight cognitive domains and a composite score, looking at group- and individual-level changes. A total of 75 FES participants and 91 healthy controls underwent cognitive assessment at baseline and follow-up. Linear mixed models were used for group-level analyses and reliable change index (RCI) analyses were used to investigate individual change. The prevalence of clinically significant impairment was explored at both time points, using a cut-off of < −1.5 SD, with significant cognitive impairment defined as impairment on ≥2 domains. Group-level analyses found main effects of group and time, and time by group interactions. Memory, psychomotor processing speed and verbal fluency improved, while learning, mental processing speed and working memory were stable in both groups. FES participants showed d
Who reads Domain-specific cognitive course in schizophrenia: Group- and individual-level changes over 10 years?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Camilla Bärthel Flaaten; Ingrid Melle; Thomas Bjella; Magnus Johan Engen; Gina Åsbø; Kristin Fjelnseth Wold; Line Widing; Erlend Gardsjord; Linn-Sofie Sæther; Merete Glenne Øie; Siv Hege Lyngstad; Beathe Haatveit; Carmen Simonsen; Torill Ueland
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)