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Can I read Association of Long-term Change in N-Terminal Pro–B-Type Natriuretic Peptide With Incident Heart Failure and Death on EtoBox?
Association of Long-term Change in N-Terminal Pro–B-Type Natriuretic Peptide With Incident Heart Failure and Death by Xiaoming Jia; Mahmoud Al Rifai; Ron Hoogeveen; Justin B. Echouffo-Tcheugui; Amil M. Shah; Chiadi E. Ndumele; Salim S. Virani; Biykem Bozkurt; Elizabeth Selvin; Christie M. Ballantyne; Vijay Nambi is a Medicine article available to read on EtoBox.
What is Association of Long-term Change in N-Terminal Pro–B-Type Natriuretic Peptide With Incident Heart Failure and Death about?
Importance Most studies, especially in primary prevention patients, have evaluated N-terminal B-type natriuretic peptide (NT-proBNP) at one time point. Evaluation of change in NT-proBNP may improve risk stratification for incident cardiovascular events. Objective To assess the association between change in NT-proBNP and risk for incident heart failure (HF) and death. Design, Setting, and Participants Participants were recruited from 4 US communities enrolled in the Atherosclerosis Risk in Community (ARIC) study. Individuals who attended ARIC visits 2 and 4 (approximately 6 years apart) with measurements of NT-proBNP and without prevalent HF were included. Assays of NT-proBNP were conducted between 2011 and 2013, and analysis took place between July 2021 and October 2022. Exposures The primary exposure variable was NT-proBNP change between visits 2 and 4, modeled as change categories (<125 pg/mL or ≥125 pg/mL) and as percent change. Main Outcomes and Measures The primary outcome measures were incident HF hospitalization and all-cause death. The association between changes in cardiovascular risk factors with change in NT-proBNP was further assessed. Results A total of 9776 individual
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- Author
- Xiaoming Jia; Mahmoud Al Rifai; Ron Hoogeveen; Justin B. Echouffo-Tcheugui; Amil M. Shah; Chiadi E. Ndumele; Salim S. Virani; Biykem Bozkurt; Elizabeth Selvin; Christie M. Ballantyne; Vijay Nambi
- Publisher
- American Medical Association (AMA)
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)