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Radiomics for differentiation of the posterior fossa pilocytic astrocytoma versus hemangioblastomas in adults. A pilot study by Houman Sotoudeh; Zahra Saadatpour; Ali Rezaei; Mahsan Sotoudeh; Charles A. Wheeler; Aparna Singhal; Manoj Tanwar is a Medicine article available to read on EtoBox.

What is Radiomics for differentiation of the posterior fossa pilocytic astrocytoma versus hemangioblastomas in adults. A pilot study about?

Purpose Both pilocytic astrocytoma (PA) and hemangioblastoma (HB) are common primary neoplasms of the posterior fossa with similar radiological manifestations. This study was conducted to evaluate the role of Radiomics in differentiating these two conditions in adults. Materials and methods After a retrospective search of our institutional imaging archive, adult patients with a known diagnosis of PA or HB were included. We reviewed each patient's most recent preoperative brain magnetic resonance imaging (MRI). The solid enhancing nodule of each lesion on post-contrast T1 sequence was manually segmented. Multiple Radiomics features were then extracted from each nodule using the Pyradiomics library. Subsequently, the most predictive features were identified by feature selection models. Following this, different machine learning (ML) models were constructed based on these selected features to classify lesions as PA or HB. Finally, we evaluated the performance of each model by leave-one-out cross-validation. Results With inclusion and exclusion criteria, 34 enhancing PA nodules and 39 HB nodules were selected. A total of 115 features were extracted from each enhancing nodule. Twelve ch

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Author
Houman Sotoudeh; Zahra Saadatpour; Ali Rezaei; Mahsan Sotoudeh; Charles A. Wheeler; Aparna Singhal; Manoj Tanwar
Publisher
Elsevier BV
Published
2023
Language
EN
Field
Medicine (Health Sciences)

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