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Can I read The natural history of idiopathic pulmonary fibrosis in a large European population: the role of age, sex and comorbidities on EtoBox?
The natural history of idiopathic pulmonary fibrosis in a large European population: the role of age, sex and comorbidities by Antonella Caminati; Fabiana Madotto; Sara Conti; Giancarlo Cesana; Lorenzo Mantovani; Sergio Harari is a Medicine article available to read on EtoBox.
What is The natural history of idiopathic pulmonary fibrosis in a large European population: the role of age, sex and comorbidities about?
Placebo arms of clinical trials provide an opportunity to investigate the natural history of idiopathic pulmonary fibrosis (IPF) but these patients are not representative of the real life IPF population. Objective of this article is to evaluate patients' characteristics of incident IPF cases and their impact on mortality and hospitalizations risk. We conducted a retrospective cohort study using data from administrative databases from 2000 to 2010. Based on different algorithms reported in literature, incident IPF cases were identified. We applied Cox proportional hazards models to assess relationship between patients' characteristics, mortality and hospitalization. According to three case definitions, we identified 2338, 460 and 1704 incident IPF cases. Mean age at diagnosis was about 72 years, the proportion of male varied between 59 and 62% and patients with at least one chronic disease were between 70 and 74%. Age, male sex and comorbidities were associated to worse outcomes. Congestive heart failure (CHF), diabetes and cancer were conditions associated to mortality, while those associated to hospitalization were CHF and chronic obstructive pulmonary disease. Our data source pro
Who reads The natural history of idiopathic pulmonary fibrosis in a large European population: the role of age, sex and comorbidities?
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- Author
- Antonella Caminati; Fabiana Madotto; Sara Conti; Giancarlo Cesana; Lorenzo Mantovani; Sergio Harari
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)