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What is TEWL and Hydrocortisone in Dermatitis about?

This study examined the relationship between transepidermal water loss (TEWL) and the absorption of hydrocortisone cream in 9 patients with widespread dermatitis. TEWL, a measure of skin barrier function, was measured at multiple sites before patients applied hydrocortisone cream. There was a highly significant correlation found between the rise in plasma cortisol levels after cream application and the mean TEWL - higher TEWL was associated with greater hydrocortisone absorption. The study suggests TEWL can

Author

Heidy Chavez

Language

EN