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CODON—Software to manual curation of prokaryotic genomes by Bruno Merlin; Jorianne Thyeska Castro Alves; Pablo Henrique Caracciolo Gomes de Sá; Mônica Silva de Oliveira; Larissa Maranhão Dias; Gislenne da Silva Moia; Victória Cardoso dos Santos; Adonney Allan de Oliveira Veras is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is CODON—Software to manual curation of prokaryotic genomes about?
Genome annotation conceptually consists of inferring and assigning biological information to gene products. Over the years, numerous pipelines and computational tools have been developed aiming to automate this task and assist researchers in gaining knowledge about target genes of study. However, even with these technological advances, manual annotation or manual curation is necessary, where the information attributed to the gene products is verified and enriched. Despite being called the gold standard process for depositing data in a biological database, the task of manual curation requires significant time and effort from researchers who sometimes have to parse through numerous products in various public databases. To assist with this problem, we present CODON, a tool for manual curation of genomic data, capable of performing the prediction and annotation process. This software makes use of a finite state machine in the prediction process and automatically annotates products based on information obtained from the Uniprot database. CODON is equipped with a simple and intuitive graphic interface that assists on manual curation, enabling the user to decide about the analysis based o
Who reads CODON—Software to manual curation of prokaryotic genomes?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Bruno Merlin; Jorianne Thyeska Castro Alves; Pablo Henrique Caracciolo Gomes de Sá; Mônica Silva de Oliveira; Larissa Maranhão Dias; Gislenne da Silva Moia; Victória Cardoso dos Santos; Adonney Allan de Oliveira Veras
- Publisher
- Public Library of Science (PLoS)
- Published
- 2021
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)