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What is ABCA1 about?

The study investigates the effects of high shear stress (HSS) on human brain microvascular endothelial cells (HBMECs) and the role of the cholesterol efflux regulator ABCA1 in mediating these effects. Results indicate that HSS decreases cell viability and migration while increasing apoptosis and inflammatory cytokine levels, with ABCA1 playing a protective role through the PI3K/Akt/eNOS signaling pathway. These findings suggest that targeting the ABCA1/PI3K/Akt/eNOS pathway may offer therapeutic potential f

Author

vpn.hk.god

Language

EN