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The document discusses protein structure determination using X-ray crystallography. It describes how two groups independently determined the structure of the cytokine IL-4 using X-ray crystallography and NMR. Both X-ray structures agreed well with each other and with NMR structures. It also discusses the determination of the structures of the proteins MutS and aquaporin, a water channel, including using selenomethionine derivatives and molecular replacement. Key aspects of protein crystallography covered in
- Author
- Amit Gupta
- Language
- EN