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Can I read Lactate dehydrogenase A mediated histone lactylation induced the pyroptosis through targeting HMGB1 on EtoBox?
Lactate dehydrogenase A mediated histone lactylation induced the pyroptosis through targeting HMGB1 by Xuan Yao; Chao Li is a Medicine article available to read on EtoBox.
What is Lactate dehydrogenase A mediated histone lactylation induced the pyroptosis through targeting HMGB1 about?
ischemia-reperfusion (CI/R) injury, which seriously affects the survival rate of patients and the functional recovery after survival . Therefore, it is particularly urgent to seek new therapeutic targets and related drugs from the pathogenesis and regulatory strategies of CI/R.Recently, CI/R has been demonstrated to induce various programs of cell death, such as necrosis, apoptosis or pyroptosis ). Among these, pyroptosis s a hot spot in recent research on CI/R injury(Zhang et al. 2022). Pyroptosis is a form of cell death characterized by both apoptosis and necrosis in morphology and pathophysiology, which is characterized by the rapid formation of plasma membrane pores, cell swelling and then osmotic necrosis, and the release of a large number of cell contents and proinflammatory mediators (Wang et al. 2020; Yu et al. 2021). Pyroptosis, as a pro-inflammatory death mode, is widely involved in the occurrence and development of many diseases
Who reads Lactate dehydrogenase A mediated histone lactylation induced the pyroptosis through targeting HMGB1?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Xuan Yao; Chao Li
- Publisher
- Springer Science and Business Media LLC
- Published
- 2023
- Language
- EN
- Field
- Medicine (Life Sciences)