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Can I read Involvement of digestive system in COVID-19: manifestations, pathology, management and challenges on EtoBox?
Involvement of digestive system in COVID-19: manifestations, pathology, management and challenges by Song Su; Jun Shen; Liangru Zhu; Yun Qiu; Jin-Shen He; Jin-Yu Tan; Marietta Iacucci; Siew C Ng; Subrata Ghosh; Ren Mao; Jie Liang is a Medicine article available to read on EtoBox.
What is Involvement of digestive system in COVID-19: manifestations, pathology, management and challenges about?
The pandemic of novel coronavirus disease (COVID-19) has developed as a tremendous threat to global health. Although most COVID-19 patients present with respiratory symptoms, some present with gastrointestinal (GI) symptoms like diarrhoea, loss of appetite, nausea/vomiting and abdominal pain as the major complaints. These features may be attributable to the following facts: (a) COVID-19 is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and its receptor angiotensin converting enzyme 2 (ACE2) was found to be highly expressed in GI epithelial cells, providing a prerequisite for SARS-CoV-2 infection; (b) SARS-CoV-2 viral RNA has been found in stool specimens of infected patients, and 20% of patients showed prolonged presence of SARS-CoV-2 RNA in faecal samples after the virus converting to negative in the respiratory system. These findings suggest that SARS-CoV-2 may be able to actively infect and replicate in the GI tract. Moreover, GI infection could be the first manifestation antedating respiratory symptoms; patients suffering only digestive symptoms but no respiratory symptoms as clinical manifestation have also been reported. Thus, the implications of
Who reads Involvement of digestive system in COVID-19: manifestations, pathology, management and challenges?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Song Su; Jun Shen; Liangru Zhu; Yun Qiu; Jin-Shen He; Jin-Yu Tan; Marietta Iacucci; Siew C Ng; Subrata Ghosh; Ren Mao; Jie Liang
- Publisher
- SAGE Publications (ISSN 1756-283X)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)