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Association of White Matter Hyperintensities with Migraine Phenotypes and Response to Treatment by Sherihan Rezk Ahmed; Amr Abdel Monem Mohamed; Haitham Hamdy Salem; Shahinaz Helmy; Ramez Reda Moustafa; Sherien Mohamed Farag Borham is a Medicine article available to read on EtoBox.
What is Association of White Matter Hyperintensities with Migraine Phenotypes and Response to Treatment about?
## Introduction White matter hyperintensities (WMHs) are frequently found in migraineurs. However, their clinical significance and correlation to different migraine phenotypes and treatment responses are not well defined. The study aimed to examine the association of WMHs with migraine clinical patterns and treatment response. ## Aim of work We aimed to evaluate the association between WMHs and migraine phenotypes and explore the relationship of WMHs to treatment response. ## Methods Our cross-sectional study formed of 500 migraineurs who sought treatment in Kafr el-sheik university hospital and underwent (3 T) MRI to evaluate WMHs. Different migraine phenotypes were compared between patients with and without WMHs. According to reduced headache pain intensity and frequency, these patients were divided into treatment responder and non-responder groups. ## Results A total of 145 patients (29%) had WMHs. Patients with WMHs were significantly older, had a longer disease duration, and higher attack frequency. Patients who did not respond to acute and maintenance medications had a higher frequency of WMHs and high WMHs Scheltens score. Migraine with Aura and the presence of vomiting and
Who reads Association of White Matter Hyperintensities with Migraine Phenotypes and Response to Treatment?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Sherihan Rezk Ahmed; Amr Abdel Monem Mohamed; Haitham Hamdy Salem; Shahinaz Helmy; Ramez Reda Moustafa; Sherien Mohamed Farag Borham
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)