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What is Granulysin Peptides for Acne Treatment about?

This study investigated the antimicrobial activity of synthetic peptides derived from granulysin against Propionibacterium acnes, the bacteria that causes acne. Twenty granulysin-derived peptides were tested in vitro, and one peptide with substitutions of aspartic acid to arginine and methionine to cysteine showed the highest antimicrobial activity against P. acnes. This peptide was also effective against other gram-positive and gram-negative bacteria. In a clinical trial of 30 acne patients applying a crea

Author

Ovienanda Kristi

Language

EN