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What is Novel Omeprazole Synthesis Insights about?

The document reviews the novel synthesis methods for omeprazole and pharmaceutical impurities of proton pump inhibitors. Omeprazole is synthesized through a reaction involving 2-(lithium methyl sulphinyl)-5-methoxy-1H benzimidazole and 2-chloro-3,5-dimethyl-4- methoxy pyridine to form a sulphide intermediate, which is then oxidized using m-CPBA to form omeprazole. The novel synthesis processes aim to achieve expected yields through short, simple processes. Several impurities of omeprazole are also identifie

Author

Harshadbhai S.Prajapati

Language

EN