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Potential celiac disease in type 1 diabetes: A multicenter study by Adriana Franzese; Dario Iafusco; Raffaella Spadaro; Olmina Cavaliere; Francesco Prisco; Renata Auricchio; Riccardo Troncone; Giuliana Valerio is a Medicine article available to read on EtoBox.

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## Aims: To describe the prevalence of potential celiac disease (pot-cd) in young patients with type 1 diabetes mellitus (t1dm) and characterize their clinical features. ## Methods: This cross-sectional multicenter study involved 8717 t1dm patients from 31 italian centers. information was collected on the total number of t1dm patients, cd patients and pot-cd patients. the following data were collected on pot-cd patients: gender, age at t1dm diagnosis, age at the first cd serological positivity, presence of cd-related symptoms, presence of other autoimmune disorders and treatment with gluten free diet (gfd). one thousand-three-hundred-sixty-one patients who were positive for cd serology were the control group. ## Results: Cd serological positivity was found in 7.2% t1dm patients. prevalence of pot-cd was 12.2% (n=77) among cd positive patients: symptoms were present in 12/77; a third autoimmune disorder was found in 15 patients. prevalence of pot-cd in the control population was 8.4% (n=114; p=0.005). no difference was found with regard to clinical features. only few symptomatic patients were on gfd both in t1dm and control patients. ## Conclusions: A higher prevalence of pot-cd was

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Author

Adriana Franzese; Dario Iafusco; Raffaella Spadaro; Olmina Cavaliere; Francesco Prisco; Renata Auricchio; Riccardo Troncone; Giuliana Valerio

Publisher

Elsevier BV

Published

2011

Language

EN

Field

Medicine (Health Sciences)