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Molecules 25 02835 V3 by . is a document available to read on EtoBox.
Selectins are adhesion molecules that play crucial roles in immune responses, inflammation, and tissue healing by mediating interactions between leukocytes and endothelial cells. They exhibit dual functions, promoting both beneficial physiological processes and harmful effects in diseases like cancer. This review discusses the structure of selectins, their interactions with glycan ligands, and their potential as therapeutic targets for inflammatory diseases and cancer.
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