About this Medicine article
Glue Versus Mechanical Mesh Fixation in Laparoscopic Inguinal Hernia Repair: Meta-analysis and Trial Sequential Analysis of Randomized Clinical Trials by N A R Habib Bedwani; M Kelada; N Smart; R Szydlo; D K Patten; A Bhargava is a Medicine article available to read on EtoBox.
## Abstract ## Background The optimal choice for mesh fixation in laparoscopic inguinal hernia repair (LIHR) has not been well established. This review compared the effects of glue versus mechanical mesh fixation in LIHR on incidence of chronic postoperative inguinal pain (CPIP) and other secondary outcomes, including acute pain, seroma, haematoma, hernia recurrence and other postoperative complications. ## Methods A systematic review of English/non-English studies using MEDLINE, the Cochrane Library, OpenGrey, OpenThesis and Web of Science, and searching bibliographies of included studies was completed. Search terms included laparoscopic, hernia, fibrin glue, Tisseel, Tissucol, cyanoacrylate, Glubran and Liquiband. Only RCTs comparing mechanical with glue-based fixation in adult patients (aged over 18 years) that examined CPIP were included. Two authors independently completed risk-of-bias assessment and data extraction against predefined data fields. All pooled analyses were computed using a random-effects model. ## Results Fifteen RCTs met the inclusion criteria; 2777 hernias among 2109 patients were assessed. The incidence of CPIP was reduced with use of glue-based fixation (ri
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- N A R Habib Bedwani; M Kelada; N Smart; R Szydlo; D K Patten; A Bhargava
- Publisher
- Oxford University Press (OUP)
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)