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Can I read 99mTc Bone-Avid Tracer Cardiac Scintigraphy: Role in Noninvasive Diagnosis of Transthyretin Cardiac Amyloidosis on EtoBox?

99mTc Bone-Avid Tracer Cardiac Scintigraphy: Role in Noninvasive Diagnosis of Transthyretin Cardiac Amyloidosis by Yiu Ming Khor; Sarah A. M. Cuddy; Vasvi Singh; Rodney H. Falk; Marcelo F. Di Carli; Sharmila Dorbala is a Medicine article available to read on EtoBox.

What is 99mTc Bone-Avid Tracer Cardiac Scintigraphy: Role in Noninvasive Diagnosis of Transthyretin Cardiac Amyloidosis about?

REVIEW O ver the last 5 years, nuclear cardiology has witnessed tremendous growth in the use of technetium 99m ( 99m Tc) bone-avid tracer cardiac scintigraphy for clinical and research applications. Its substantial clinical value for evaluation of patients with heart failure with preserved ejection fraction (HFpEF) has motivated many hospitals to start cardiac amyloidosis imaging programs. However, experience with performance, interpretation, and reporting of 99m Tc bone-avid tracer cardiac scintigraphy remains limited. High-quality scan acquisition, accurate interpretation, and definitive reporting are critical for realization of the full potential of this modality. This review will provide an overview of cardiac amyloidosis, summarize the emerging literature on bone-avid tracer cardiac scintigraphy, and illustrate a step-by-step approach to accurate interpretation and reporting of 99m Tc bone-avid tracer cardiac scintigraphy findings. Cardiac Amyloidosis Amyloidoses are protein misfolding disorders characterized by extracellular deposition of insoluble amyloid fibrils in various organs, including the heart (1). Amyloid deposits in the myocardium expand the extracellular space, in

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Author
Yiu Ming Khor; Sarah A. M. Cuddy; Vasvi Singh; Rodney H. Falk; Marcelo F. Di Carli; Sharmila Dorbala
Publisher
Radiological Society of North America (RSNA)
Published
2023
Language
EN
Field
Medicine (Health Sciences)

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