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Can I read Human Inter-α-Trypsin Inhibitor: Localization of the Kunitz-Type Domains in the N-terminal Part of the Molecule and their Release by a Trypsin-Like Proteinase on EtoBox?
Human Inter-α-Trypsin Inhibitor: Localization of the Kunitz-Type Domains in the N-terminal Part of the Molecule and their Release by a Trypsin-Like Proteinase by REISINGER, Peter; HOCHSTRASSER, Karl; ALBRECHT, Gerd J.; LEMPART, Kathrin; SALIER, Jean-Philippe is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Human Inter-α-Trypsin Inhibitor: Localization of the Kunitz-Type Domains in the N-terminal Part of the Molecule and their Release by a Trypsin-Like Proteinase about?
The N-terminal amino-acid sequence of human ITI has been found to be identical with that of the acid-stable human 30-kDa inhibitors (HI-30) from urine, serum, and those released from inter-a-trypsin inhibitor by trypsin or chymotrypsin. Serum HI-30 and HI-30 released by trypsin differ from the urinary inhibitor by an additional C-terminal arginine residue. Compared to these two inhibitors the inhibitor released by chymotryptic proteolysis is elongated C-terminally by an additional phenylalanine residue. These results strongly favour HI-30 as the N-terminus of the inter-a-trypsin inhibitor and its release from this inhibitor in vivo by cleavage of the Arg 123 -Phe 124 peptide bond by trypsin-like proteinases.
Who reads Human Inter-α-Trypsin Inhibitor: Localization of the Kunitz-Type Domains in the N-terminal Part of the Molecule and their Release by a Trypsin-Like Proteinase?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- REISINGER, Peter; HOCHSTRASSER, Karl; ALBRECHT, Gerd J.; LEMPART, Kathrin; SALIER, Jean-Philippe
- Publisher
- Walter de Gruyter GmbH (ISSN 0177-3593)
- Published
- 1985
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)