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Haplotype frequencies of 16 Y-chromosome STR loci in the Barcelona metropolitan area population using Y-FilerTM kit by C. Sánchez; C. Barrot; A. Xifró; M. Ortega; I. Gómez de Aranda; E. Huguet; J. Corbella; M. Gené is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Haplotype frequencies of 16 Y-chromosome STR loci in the Barcelona metropolitan area population using Y-FilerTM kit about?

Haplotype frequencies for 16 Y-chromosomal short tandem repeat (STR) loci, included in the Y-Filer TM kit, were determined in 247 unrelated healthy individuals from the Barcelona metropolitan area (Catalonia, NE Spain). After PCR amplification and denaturing PAGE electrophoresis, DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385a/b, DYS393, DYS391, DYS439, DYS635, DYS392, Y GATA H4.1, DYS437, DYS438 and DYS448 loci were typed. The aim of this study is to evaluate the performance in our population of the 16 loci of the Y-chromosome present in the new Y-Filer TM commercial identification kit, and acquire haplotype frequencies for mathematic processing of the forensic diagnosis in our geographical working area. In this sample, all haplotypes were unique. From the forensic point of view, the combined polymorphisms of the Y-Filer TM kit provide a high diagnostic efficiency.

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Author

C. Sánchez; C. Barrot; A. Xifró; M. Ortega; I. Gómez de Aranda; E. Huguet; J. Corbella; M. Gené

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0379-0738)

Published

2007

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)