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Comparison of low and high dose rate brachytherapy in the treatment of uterine cervix cancer. Retrospective analysis of two sequential series by Robson Ferrigno; Ines Nobuko Nishimoto; Paulo Eduardo Ribeiro dos Santos Novaes; Antonio Cássio Assis Pellizzon; Maria Aparecida Conte Maia; Ricardo César Fogarolli; João Victor Salvajoli is a Medicine article available to read on EtoBox.
What is Comparison of low and high dose rate brachytherapy in the treatment of uterine cervix cancer. Retrospective analysis of two sequential series about?
Purpose: This retrospective analysis aims to report on the comparative outcome of cervical cancer patients treated with low dose rate (LDR) and high dose rate (HDR) brachytherapy. Methods and Materials: From 1989 to 1995, 190 patients were treated with low dose rate (LDR) brachytherapy (LDR group) and from 1994 to 2001, 118 patients were treated with high dose rate (HDR) brachytherapy (HDR group). FIGO stage distribution for the LDR group was Stage I: 6.3%; Stage II: 57.4%; and Stage III: 36.3% and for the HDR group Stage I: 9.3%; Stage II: 43.2%; and Stage III: 47.4%. All patients were treated with telecobalt external-beam radiotherapy (EBR). Median doses of LDR brachytherapy at Point A were 40 Gy and 50 Gy for patients treated with 1 and 2 implants, respectively. All patients from the HDR group were treated with 24 Gy in 4 fractions of 6 Gy to Point A. Survival, disease-free survival, local control, and late complications at 5 years, were endpoints compared for both groups. Results: Median follow-up time for LDR and HDR groups was 70 months (range, 8 -127 months) and 33 months (range, 4 -117 months), respectively. For all stages combined, overall survival, disease-free survival,
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- Author
- Robson Ferrigno; Ines Nobuko Nishimoto; Paulo Eduardo Ribeiro dos Santos Novaes; Antonio Cássio Assis Pellizzon; Maria Aparecida Conte Maia; Ricardo César Fogarolli; João Victor Salvajoli
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)
- Published
- 2005
- Language
- EN
- Field
- Medicine (Health Sciences)