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Probing oxidative stress in single erythrocytes with Raman Tweezers by E. Zachariah; A. Bankapur; C. Santhosh; M. Valiathan; D. Mathur is a Medicine article available to read on EtoBox.

What is Probing oxidative stress in single erythrocytes with Raman Tweezers about?

Raman Tweezers have been successfully applied to characterize chemically-induced oxidative stress on optically-trapped live, single erythrocytes. There is significant enhancement in Raman peak intensities corresponding to S@S and C-S stretching modes that are induced by oxidative stress. This is consistent with the formation of mixed disulphides between protein SH groups and low-molecular-mass thiols such as glutathione during oxidative damage to cells. Enhancement in glutathione level as a protective response against oxidative stress has been observed. Principal component analysis of the data yields good discrimination between spectra of normal and stress-induced red blood cells.

Who reads Probing oxidative stress in single erythrocytes with Raman Tweezers?

Author

E. Zachariah; A. Bankapur; C. Santhosh; M. Valiathan; D. Mathur

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1011-1344)

Published

2010

Language

EN

Field

Medicine (Physical Sciences)