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The Effect of Probiotic Supplementation on Episiotomy Wound Healing Among Primiparous Women: a Triple-blind Randomized Clinical Trial by Derakhshan Abdollahpour; Aziz Homayouni-Rad; Roghaiyeh Nourizadeh; Sevil Hakimi; Esmat Mehrabi is a Medicine article available to read on EtoBox.
What is The Effect of Probiotic Supplementation on Episiotomy Wound Healing Among Primiparous Women: a Triple-blind Randomized Clinical Trial about?
## Background Probiotics increase the defense power of immune system and accelerate the wound healing process by anti-inflammatory mechanisms at the wound site. The present study aimed at evaluating the effect of Lactobacillus casei oral supplementation on episiotomy wound healing among primiparous women. ## Methods This triple-blind randomized clinical trial was performed on 74 primiparous women delivered in Alzahra Hospital, Tabriz, Iran. Participants with mediolateral episiotomy (incision length equal to and less than 5 cm) were randomly assigned to the probiotic and placebo groups. The probiotic group received Lactobacillus casei 431 with 1.5 \* 10^9^ colony-forming unit /capsule once a day from the day after birth to 14 days. Wound healing as a primary outcome was measured by Redness, Edema, Ecchymosis, Discharge, Approximation and pain as a secondary outcome by the Visual Analogue Scale before discharge, 5 ± 1 and 15 ± 1 days after birth. The data were analyzed using independent t-test and repeated measures one way analysis of variance. ## Results The mean (standard deviation: SD) score of wound healing in the probiotic group altered from 4.91(1.86) before discharge to 1.55 (
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- Author
- Derakhshan Abdollahpour; Aziz Homayouni-Rad; Roghaiyeh Nourizadeh; Sevil Hakimi; Esmat Mehrabi
- Publisher
- Springer Science and Business Media LLC
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)