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Prospective study of clinical, biochemical, and radiological characteristics of diabetic Charcot neuroarthropathy at a tertiary care centre by M. Aruna; Padala Ravi Kumar; Deepak Kumar Dash; Debasish Patro; T. Radhakrishna; Manas Ranjan Kundu; Sudhi Ranjan Pattanaik is a Medicine article available to read on EtoBox.
What is Prospective study of clinical, biochemical, and radiological characteristics of diabetic Charcot neuroarthropathy at a tertiary care centre about?
Objective The aim of this study was to assess demographic, clinical, biochemical, radiological profile and treatment response in diabetic patients with Charcot neuroarthropathy (CN). Methods This was a prospective study for screening of CN in patients with diabetes mellitus (DM) attending tertiary care centre over a period of 1 year. Acute CN (ACN) was diagnosed based on clinical features of local inflammation and temperature difference of > 2 °C from the normal foot after exclusion of other inflammatory causes. Chronic CN (CCN) was diagnosed when no inflammatory signs were present in a deformed foot with radiological findings supportive of diagnosis. In all these patients, demographic data, clinical features, biochemical investigations, X-ray, and MRI foot were done. The effect of offloading and customized foot wear in ACN, CCN were, respectively, studied over 1 year. Results Out of 5049 DM patients screened for CN over 1 year, 25 patients (0.49%) were diagnosed to have CN, of which 12 had ACN (0.23%) and 13 had CCN (0.26%). CN patients had significantly higher mean body mass index (BMI) (27.9 vs. 26.2 kg/m 2 ; p = 0.02), longer duration of DM (12 vs. 9.6 years; p < 0.001), higher
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- Author
- M. Aruna; Padala Ravi Kumar; Deepak Kumar Dash; Debasish Patro; T. Radhakrishna; Manas Ranjan Kundu; Sudhi Ranjan Pattanaik
- Publisher
- Springer Science and Business Media LLC
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)