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Necrotizing Gangrene of the Genitalia and Perineum by Hugo Cabrera; Luis Skoczdopole; Mario Marini; Patricia Della Giovanna; Alberto Saponaro; Cristina Echeverría is a Medicine article available to read on EtoBox.
What is Necrotizing Gangrene of the Genitalia and Perineum about?
## Abstract **Background** Necrotizing gangrene of the genitalia and perineum is a fulminant, life‐threatening condition. This infection is usually polymicrobial and may be idiopathic or secondary to local trauma or surgery. Histologically, it is characterized by obliterative endarteritis and thrombosis of the subcutaneous vessels, fascial necrosis, and leukocytic infiltration. Mortality rates of 25–75% have been reported. Most cases of necrotizing gangrene begin insidiously, with scrotal discomfort and malaise. Later, erythema, increasing pain, and swelling, associated with fever and chills, develop. A biopsy is useful to confirm the clinical diagnosis and to obtain culture samples. Ultrasound imaging may reveal gas or testicular involvement and may help to distinguish this infection from other causes of scrotal pathology. **Materials and methods** Fifteen patients with necrotizing gangrene of the genitalia and perineum, seen at the Dermatology and Plastic Surgery Sections of our Institutions between 1994 and 1999, are described. **Results** This series included 11 men (73%) and four women (27%), aged 39–68 years (mean, 51 years). In our series, __Clostridium perfingens__, __Staph
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- Author
- Hugo Cabrera; Luis Skoczdopole; Mario Marini; Patricia Della Giovanna; Alberto Saponaro; Cristina Echeverría
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0011-9059)
- Published
- 2002
- Language
- EN
- Field
- Medicine (Health Sciences)