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Computerized Image Analysis Software for the Comet Assay by Keohavong, Phouthone; Grant, Stephen G. is a scholarly article available to read on EtoBox.

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New State-of-the-art Molecular Techniques Promise To Transform The Field Of Genetic Toxicology By Making It Possible To Directly Detect Genotoxic Exposures And Their Consequences In Humans, To Identify The Agent(s) Involved, And To Clinically Manage The Exposed Population. In Molecular Toxicology Protocols, Researchers From Prominent Universities And Cancer Centers Around The World Describe In Detail Their Best Techniques For Analyzing Genotoxic Exposure And The Resulting Biological Effects, Including Intermediate Biomarkers Such As Dna And Chromosomal Damage, Mutations In Reporter And Oncogenes, And The Earliest Possible Detection Of Cancer. The Authors Emphasize Analytical Methods Specifically Developed For Use In Human Populations And In Cancer Patients, Or In Other In Vivo Systems Such As Transgenic Mice. Among The Applications Detailed Are The Analysis Of Interactions Of Chemical And Physical Agents With Cellular Macromolecules, Especially Dna, The Assessment Of Medically Relevant Toxicity, And The Individualized Characterization Of Genetic Damage And Repair. There Are Also Methods To Assess And Characterize The Modulation Of This Damage And Repair Through Individual Differenc

Author

Keohavong, Phouthone; Grant, Stephen G.

Publisher

Humana Press

Published

2004

Language

EN

ISBN

9781592598403