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Time to Disease Recurrence in Noninfectious Uveitis Following Long-acting Injectable Fluocinolone Acetonide Implant by Cindy X. Cai; Cindy Skalak; Robert T. Keenan; Dilraj S. Grewal; Glenn J. Jaffe is a Medicine article available to read on EtoBox.

What is Time to Disease Recurrence in Noninfectious Uveitis Following Long-acting Injectable Fluocinolone Acetonide Implant about?

## Purpose: To determine the time to disease recurrence with long-acting injectable fluocinolone acetonide implant (fai) for noninfectious intermediate, posterior, and panuveitis. ## Methods: This was a retrospective study of patients with at least 12 months of follow-up who had completed a 2-year prospective, investigational new drug study with 0.18-mg fai. time to uveitis recurrence or cystoid macular edema (cme) occurrence was recorded. ## Results: Twelve eyes from 12 participants (mean age 43 years, range 25-64 years) were included. patients were followed for a mean of 34.2 months (range, 12.0-56.9 months) after completion of the prospective trial. five eyes (42%) did not have a documented uveitis recurrence or cme occurrence. five eyes (42%) had a uveitis recurrence with the mean time to recurrence 36.1 months (range, 22.8-61.1 months) after fai implantation. two eyes (16%) had cme alone, the mean time to occurrence 36.9 months (range 36.1-42.1 months). on kaplan-meier analysis, the estimated probability of remaining recurrence-free 36 months after fai implantation was 0.67 (95% confidence interval, 0.34-0.86). ## Conclusions: Data of study participants after completing a clin

Who reads Time to Disease Recurrence in Noninfectious Uveitis Following Long-acting Injectable Fluocinolone Acetonide Implant?

Author

Cindy X. Cai; Cindy Skalak; Robert T. Keenan; Dilraj S. Grewal; Glenn J. Jaffe

Publisher

Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0065-6100)

Published

2020

Language

EN

Field

Medicine (Health Sciences)