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Inhibitory Effects of a Gradient Static Magnetic Field on Normal Angiogenesis by Zhe Wang; Pengfei Yang; Huiyun Xu; Airong Qian; Lifang Hu; Peng Shang is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Inhibitory Effects of a Gradient Static Magnetic Field on Normal Angiogenesis about?

## Abstract Angiogenesis, the formation of new blood vessels, is critical in many normal and pathological processes such as development, reproduction, tumor growth, and metastasis. Recently, exposure to moderate‐intensity static magnetic fields (1 mT to 1 T) has attracted much attention for its potential therapeutic value as a noninvasive intervening method. Nevertheless, the effects of moderate‐intensity and spatial gradient static magnetic fields (GSMF) on angiogenesis have not received enough attention. In this study, the effects of GSMF (0.2–0.4 T, 2.09 T/m, 1–11 days) on angiogenesis were investigated both in vitro and in vivo. An MTT assay was used as an in vitro method to detect the proliferation ability of human umbilical veins endothelial cells (HUVECs). Two kinds of in vivo models, a chick chorioallantoic membrane (CAM) and a matrigel plug, were used to detect the effects of GSMF on angiogenesis. The results showed that the proliferation ability of HUVECs was significantly inhibited 24 h after the onset of exposure. With regard to the CAM model, vascular numbers in the CAM that was continuously exposed to the GSMF were all less than those in normal condition. In accordanc

Who reads Inhibitory Effects of a Gradient Static Magnetic Field on Normal Angiogenesis?

Author

Zhe Wang; Pengfei Yang; Huiyun Xu; Airong Qian; Lifang Hu; Peng Shang

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0197-8462)

Published

2009

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)