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Can I read Effectiveness of Bivalent Boosters against Severe Omicron Infection on EtoBox?
Effectiveness of Bivalent Boosters against Severe Omicron Infection by Dan-Yu Lin; Yangjianchen Xu; Yu Gu; Donglin Zeng; Bradford Wheeler; Hayley Young; Shadia K. Sunny; Zack Moore is a Medicine article available to read on EtoBox.
What is Effectiveness of Bivalent Boosters against Severe Omicron Infection about?
2022, the Food and Drug Administration (FDA) authorized the Moderna and Pfizer-BioNTech bivalent Covid-19 vaccines, each containing equal amounts of mRNA encoding the spike protein from the ancestral strain and the spike protein from the BA.4 and BA.5 strains of the B.1.1.529 (omicron) variant, for emergency use as a single booster dose at least 2 months after primary or booster vaccination. 1 The FDA authorizations were based on nonclinical data for these two bivalent vaccines, safety and immunogenicity data for bivalent vaccines containing mRNA from the BA.1 lineage of the omicron variant, and safety and effectiveness data for the monovalent mRNA Covid-19 vaccines. 1 Since September 1, these two bivalent mRNA vaccines have replaced their monovalent counterparts as booster doses for persons 12 years of age or older in the United States and in other countries. Here, we report data from a large cohort study on the effectiveness of these two bivalent vaccines against severe infection with omicron BA.4.6, BA.5, BQ.1, and BQ.1.1.The data sources for this study have been described elsewhere. [2][3][4] We focused on new data collected over 99 days during which bivalent boosters were admi
Who reads Effectiveness of Bivalent Boosters against Severe Omicron Infection?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Dan-Yu Lin; Yangjianchen Xu; Yu Gu; Donglin Zeng; Bradford Wheeler; Hayley Young; Shadia K. Sunny; Zack Moore
- Publisher
- Massachusetts Medical Society
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)