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Clinical Value of Subclinical Seizures in Children with Focal Epilepsy by Ábel Velkey; Zsuzsanna Siegler; József Janszky; Borbála Duray; András Fogarasi is a Medicine article available to read on EtoBox.

What is Clinical Value of Subclinical Seizures in Children with Focal Epilepsy about?

Purpose: Subclinical seizures (SCSs) are ictal electrographic discharges lacking clinical seizure signs or subjective symptoms. In this study, frequency, characteristics and diagnostic relevance of SCSs recorded by scalp-EEG were analyzed in a large population of children with focal epilepsy. Methods: Long-term monitoring (LTM) database of 322 consecutive patients <18 years with focal epilepsy were assessed. Video-EEG data of all children with SCS were re-analyzed. Results: Fifty-nine of 322 (18%) children showed SCS on scalp-EEG, nine (15%) of them had no clinical seizures during LTM. Duration of epilepsy (5.2 vs. 6.9 years; p = 0.019) as well as length of LTM (2.8 vs. 3.6 days; p < 0.001) were longer in children with SCS. Neither sex, age at onset, age at LTM, nor focus localization showed significant difference. In 85% of cases the presence of SCS had supplementary value during the diagnostic process. It assisted localizing the seizure onset zone in 53%, suggested multiple seizure onset zones in 20% and influenced antiepileptic drug therapy in 12% of cases. Discussion: Scalp-EEG SCS in children with focal epilepsy is a frequent and important phenomenon. Although our therapeutic

Who reads Clinical Value of Subclinical Seizures in Children with Focal Epilepsy?

Author

Ábel Velkey; Zsuzsanna Siegler; József Janszky; Borbála Duray; András Fogarasi

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0920-1211)

Published

2011

Language

EN

Field

Medicine (Health Sciences)