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Can I read In vivo studies of carnitine and fatty acid metabolism: Problems with use of anesthetics on EtoBox?
In vivo studies of carnitine and fatty acid metabolism: Problems with use of anesthetics by Eric P. Brass; Charles L. Hoppel is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is In vivo studies of carnitine and fatty acid metabolism: Problems with use of anesthetics about?
The use of ether anesthesia as a technique for obtaining liver tissue and plasma from living rats was compared to decapitation followed by in situ sample freezing. Parameters associated with fatty acid metabolism were examined to demonstrate differences in the two methodologies. Use of ether in fasted rats was associated with lower plasma free fatty acids and acetoacetate concentrations, as well as decreased hepatic total camitine, camitine, and acid-soluble acylcamitine content when compared to decapitated animals. No qualitative differences between the ether and decapitated groups were noted, and the quantitative differences observed were consistent with effects induced by the anesthetic. Thus, with respect to in vivo studies of fatty acid metabolism use of anesthetic agents may induce significant changes without providing advantages over decapitation and in situ freezing.
Who reads In vivo studies of carnitine and fatty acid metabolism: Problems with use of anesthetics?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Eric P. Brass; Charles L. Hoppel
- Publisher
- Elsevier Science; Elsevier ; Elsevier Inc.; Elsevier BV (ISSN 0003-2697)
- Published
- 1981
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)