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Characteristics of the Optic Disc in Young People with High Myopia by Zhang, Fen (author);Liu, Xinting (author);Wang, Yanli (author);Wang, Qian (author);Zheng, Miaoran (author);Chang, Feng (author);Mao, Xinjie (author) is a Medicine article available to read on EtoBox.

What is Characteristics of the Optic Disc in Young People with High Myopia about?

## Abstract ## Purpose This study aimed to investigate the characteristics of the optic disc in adolescents and young adults with high myopia by applying optical coherence tomography angiography. ## Methods A total of 112 patients with high myopia (spherical equivalent refraction (SER) ≤ -6.00 D) aged 12 to 30 years old were enrolled in this cross-sectional study. Parapapillary atrophy (PPA) and ovality index from scanning laser ophthalmoscopy images and the degree of optic disc tilt from the optic nerve head (ONH) OCT B-scans were analysed using ImageJ and MATLAB software. Peripapillary retinal nerve fibre layer thickness (pRNFLT) and radial peripapillary capillary vessel density (RPC VD) around the optic disc were obtained from the images of the optic disc angiography scan. ## Results In young high myopia patients, the PPA area was positively correlated with age, axial length (AL) and pRNFLT (all p < 0.05) and negatively correlated with SER (r = -0.222, p = 0.020). The degree of the optic disc tilt was associated with increasing AL and pRNFLT (all p < 0.05). The disc area was positively correlated with AL, pRNFLT, and RPC VD (all p < 0.05). In the multivariate regression analysis

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Author

Zhang, Fen (author);Liu, Xinting (author);Wang, Yanli (author);Wang, Qian (author);Zheng, Miaoran (author);Chang, Feng (author);Mao, Xinjie (author)

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Medicine (Health Sciences)