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Identification of bioactive metabolites and evaluation of in vitro anti-inflammatory and in vivo antinociceptive and antiarthritic activities of endophyte fungi isolated from Elaeocarpus floribundus blume by Kishor Mazumder; Yasmeen Nazim Ruma; Rasheda Akter; Asma Aktar; Mir Monir Hossain; Zinnat Shahina; Santosh Mazumdar; Philip G. Kerr is a Agricultural and Biological Sciences article available to read on EtoBox.

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## Ethnopharmacological relevance: Functional disability associated with rheumatoid arthritis (ra), a chronic inflammatory autoimmune disease is a challenging concern in healthcare systems. along with environmental factors and epigenetic disorders, multiple pathways are reported as prominent mechanism for the progression of ra symptoms including; pain, swelling and stiffness of joints. elaeocarpus floribundus blume has been used as a folklore medicine for ra from ancient times. this plant harbours a suite of endophytic fungi that produce a range of metabolites of potential interest. thus, for the establishment of a scientific basis for this folklore use, it is essential to find out the involvement, if any, of the endophytic fungi living in this plant and the metabolites they elaborate, for the management of ra. ## Aim of the study: This study was designed to isolate, identify and evaluate the in vitro anti-inflammatory and in vivo antinociceptive and antiarthritic activities of the compounds produced by the endophytic fungi living in different parts of elaeocarpus floribundus blume. ## Materials and methods: Endophytic fungi from different parts of the plant were isolated and cultu

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Author

Kishor Mazumder; Yasmeen Nazim Ruma; Rasheda Akter; Asma Aktar; Mir Monir Hossain; Zinnat Shahina; Santosh Mazumdar; Philip G. Kerr

Publisher

Elsevier BV

Published

2021

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)