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Cochrane review: Extracorporeal membrane oxygenation for severe respiratory failure in newborn infants by Miranda Mugford; Diana Elbourne; David Field is a Medicine article available to read on EtoBox.

What is Cochrane review: Extracorporeal membrane oxygenation for severe respiratory failure in newborn infants about?

## Abstract ## Background Neonatal extracorporeal membrane oxygenation (ECMO) is a complex procedure of life support used in severe but potentially reversible respiratory failure in term infants. Although the number of babies eligible for ECMO is small and the use of ECMO invasive and potentially expensive, its benefits may be high. ## Objectives To determine whether ECMO used for neonatal infants with severe respiratory failure is clinically and cost effective compared to conventional ventilatory support. ## Search strategy The Cochrane Neonatal Group Specialised Register, the Cochrane Controlled Trials Register, and MEDLINE were searched for 1974 to 2007. ## Selection criteria All randomised trials comparing neonatal ECMO to conventional ventilatory support. ## Data collection and analysis The authors independently evaluated the trials for methodological quality and appropriateness for inclusion in the Review (without consideration of their results) and independently extracted the data. ## Main results The four trials (three USA and one UK) recruited clinically similar groups of babies. Two trials excluded infants with congenital diaphragmatic hernias. In two trials, transfer for

Who reads Cochrane review: Extracorporeal membrane oxygenation for severe respiratory failure in newborn infants?

Author

Miranda Mugford; Diana Elbourne; David Field

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley and Sons Ltd; Wiley (ISSN 1557-6272)

Published

2010

Language

EN

Field

Medicine (Health Sciences)