Can I read Current Progress in Neural Crest Cell Motility and Migration and Future Prospects for the Zebrafish Model System on EtoBox?

Current Progress in Neural Crest Cell Motility and Migration and Future Prospects for the Zebrafish Model System by Mary C. Halloran; Jason D. Berndt is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Current Progress in Neural Crest Cell Motility and Migration and Future Prospects for the Zebrafish Model System about?

## Abstract The neural crest is a unique population of cells that contributes to the formation of diverse cell types, including craniofacial cartilage, peripheral neurons, the cardiac outflow tract, and pigment cells. Neural crest cells (NCCs) are specified within the neuroepithelium, undergo an epithelial‐to‐mesenchymal transition, and migrate to target destinations throughout the embryo. Here, we review current understanding of two steps in NCC development, both of which involve NCC motility. The first is NCC delamination from the neuroepithelium and the changes in cell adhesion and the cytoskeleton necessary for the initiation of migration. The second is NCC migration and the signals that guide NCCs along specific migratory pathways. We illustrate the strength of the zebrafish, __Danio rerio__, as a model organism to study NCC motility. The zebrafish is particularly well suited for the study of neural crest motility because of the ability to combine genetic manipulation with live imaging of migrating NCCs. Developmental Dynamics, 2003. © 2003 Wiley‐Liss, Inc.

Who reads Current Progress in Neural Crest Cell Motility and Migration and Future Prospects for the Zebrafish Model System?

Author

Mary C. Halloran; Jason D. Berndt

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1058-8388)

Published

2003

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)