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Effects of Aging and Lifelong Aerobic Exercise on Basal and Exercise-Induced Inflammation in Women by Lavin, Kaleen M.; Perkins, Ryan K.; Jemiolo, Bozena; Raue, Ulrika; Trappe, Scott W.; Trappe, Todd A. is a Medicine article available to read on EtoBox.
What is Effects of Aging and Lifelong Aerobic Exercise on Basal and Exercise-Induced Inflammation in Women about?
Low muscle mass and frailty are especially prevalent in older women and may be accelerated by age-related inflammation. Habitual physical activity throughout the life span (lifelong exercise) may prevent muscle inflammation and associated pathologies, but this is unexplored in women. This investigation assessed basal and acute exercise-induced inflammation in three cohorts of women: young exercisers (YE, = 10, 25 ± 1 yr, [Formula: see text]: 44 ± 2 mL/kg/min, quadriceps size: 59 ± 2 cm), old healthy nonexercisers (OH, = 10, 75 ± 1 yr, [Formula: see text]: 18 ± 1 mL/kg/min, quadriceps size: 40 ± 1 cm), and lifelong aerobic exercisers with a 48 ± 2 yr aerobic training history (LLE, = 7, 72 ± 2 yr, [Formula: see text]: 26 ± 2 mL/kg/min, quadriceps size: 42 ± 2 cm). Resting serum IL-6, TNF-α, C-reactive protein (CRP), and IGF-1 were measured. Vastus lateralis muscle biopsies were obtained at rest (basal) and 4 h after an acute exercise challenge (3 × 10 reps, 70% 1-repetition maximum) to assess gene expression of cytokines (IL-6, TNF-α, IL-1β, IL-10, IL-4, IL-1Ra, TGF-β), chemokines (IL-8, MCP-1), cyclooxygenase enzymes (COX-1, COX-2), prostaglandin E synthases (mPGES-1, cPGES) and rec
Who reads Effects of Aging and Lifelong Aerobic Exercise on Basal and Exercise-Induced Inflammation in Women?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Lavin, Kaleen M.; Perkins, Ryan K.; Jemiolo, Bozena; Raue, Ulrika; Trappe, Scott W.; Trappe, Todd A.
- Publisher
- The American Physiological Society; American Physiological Society (ISSN 8750-7587)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)