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The study investigates the effects of the selective cyclooxygenase-2 inhibitor NS-398 on intrafollicular PGE2 synthesis and ovulation in dairy cattle. Results show that NS-398 significantly reduces PGE2 concentrations and inhibits follicle rupture, leading to a failure of ovulation in most treated animals. The findings suggest that ultrasound-mediated intrafollicular injection of NS-398 is a valuable method for studying the regulation of ovulation in cattle.

Author
Cynthia Marchetti
Language
EN

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