Opening book details…
Can I read Efficacy and safety of a 14‐day modified concomitant therapy for refractory Helicobacter pylori infection: a pilot study on EtoBox?
Efficacy and safety of a 14‐day modified concomitant therapy for refractory Helicobacter pylori infection: a pilot study by Shu‐yan Zeng; Juan Wang; Jing Liu; Min‐Juan Lin; Bo‐Shen Lin; Yu‐Ming Ding; Qing‐Zhou Kong; Wen‐Lin Zhang; Miao Duan; Zhong‐Xue Han; Yue‐yue Li; Xiu‐Li Zuo; Yan‐Qing Li is a Medicine article available to read on EtoBox.
What is Efficacy and safety of a 14‐day modified concomitant therapy for refractory Helicobacter pylori infection: a pilot study about?
## Abstract ## Background and Aim After three treatment failures, __Helicobacter pylori__ infection is deemed refractory as antibiotic treatment options become significantly limited. This study evaluated the efficacy and safety of a 14‐day modified concomitant therapy for managing refractory __H. pylori__ infection. ## Methods Patients who had failed to respond to three or more rounds of __H. pylori__ therapies were recruited for this study. They received a 14‐day modified concomitant therapy, including esomeprazole 40 mg, amoxicillin 1000 mg, and furazolidone 100 mg twice daily and tetracycline 500 mg four times daily. Demographic data, adverse events, and patient compliance were recorded. The presence of __H. pylori__ was reevaluated 6 weeks following treatment. Eradication rate was assessed as the primary outcome. ## Results Overall, 59 participants received the 14‐day modified concomitant therapy. In the intention‐to‐treat and per‐protocol analyses, the eradication rate was 84.7% (50/59) and 89.3% (50/56), respectively. __H. pylori__ was successfully isolated from 75.0% (12/16) of patients. The resistance rate of __H. pylori__ to metronidazole, levofloxacin, and clarithromycin
Who reads Efficacy and safety of a 14‐day modified concomitant therapy for refractory Helicobacter pylori infection: a pilot study?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Shu‐yan Zeng; Juan Wang; Jing Liu; Min‐Juan Lin; Bo‐Shen Lin; Yu‐Ming Ding; Qing‐Zhou Kong; Wen‐Lin Zhang; Miao Duan; Zhong‐Xue Han; Yue‐yue Li; Xiu‐Li Zuo; Yan‐Qing Li
- Publisher
- Wiley
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)