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Short Course of Prednisolone in Indian Patients with Solitary Cysticercus Granuloma and New-onset Seizures by Ravi Kant Mall; Atul Agarwal; Ravindra Kumar Garg; Alok Mohan Kar; Rakesh Shukla is a Medicine article available to read on EtoBox.
What is Short Course of Prednisolone in Indian Patients with Solitary Cysticercus Granuloma and New-onset Seizures about?
**Summary:** __Purpose:__ To evaluate the role of a short course of oral corticosteroids in Indian patients with solitary cysticercus granuloma with seizures. __Methods:__ In this open‐label, randomized, prospective follow‐up study, 97 patients with new‐onset seizures and a single enhancing computed tomography (CT)‐detected lesion of cysticercosis were randomly divided in two groups to receive either antiepileptic monotherapy alone (n = 48) or antiepileptic monotherapy with prednisolone (n = 49). The patients in the latter group received prednisolone, 1 mg/kg/day for 10 days, followed by tapering over next 4 days. The patients were followed up for 6 months. Repeated CT scans were performed after 1 and 6 months. __Results:__ The majority of patients were young. Simple partial seizure, with or without secondary generalization, was the commonest seizure type encountered. Follow‐up CT scans at 1 and 6 months demonstrated a significantly better response for prednisolone as far as complete resolution of CT lesion was concerned. Kaplan–Meier analysis suggested significantly less probability of seizure recurrence for prednisolone‐treated patients. At 6 months, Kaplan–Meier estimated risk o
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It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Ravi Kant Mall; Atul Agarwal; Ravindra Kumar Garg; Alok Mohan Kar; Rakesh Shukla
- Publisher
- Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0013-9580)
- Published
- 2003
- Language
- EN
- Field
- Medicine (Health Sciences)