About this document
BMC Neuroscience: Requirements For A Lead Compound To Become A Clinical Candidate by dasdee is a document available to read on EtoBox.
This document discusses the requirements for a lead compound to become a clinical drug candidate. It must selectively bind to the target receptor and elicit the desired functional response. It also needs adequate bioavailability and biodistribution to produce effects in animals and humans. Most importantly, it must pass formal toxicity evaluation in animals to demonstrate minimal risk to human subjects in clinical studies.
- Author
- dasdee
- Language
- EN