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Selective Reduction of Oscillatory Potentials and Pattern Electroretinograms After Retinal Ganglion Cell Damage by Disease in Humans or by Kainic Acid Toxicity in Cats by Vaegan; S. L. Graham; I. Goldberg; T. J. Millar is a Medicine article available to read on EtoBox.
What is Selective Reduction of Oscillatory Potentials and Pattern Electroretinograms After Retinal Ganglion Cell Damage by Disease in Humans or by Kainic Acid Toxicity in Cats about?
We recorded pattern electroretinograms, scotopic threshold responses, oscillatory potentials and ganzfeld flash electroretinograms in patients with glaucoma or other optic nerve diseases and in cats with inner retinal damage caused by intravitreal injections of kainic acid. In both studies, the scotopic b-wave and the scotopic threshold responses were normal but the oscillatory potentials and pattern electroretinograms were not. The photopic b-wave was also often reduced in patients with scotopic oscillatory potential reduction, and the reduction was proportionate to the oscillatory potential change. Oscillatory potentials were as frequently reduced as pattern electroretinograms in both patient groups, and in the few cases where only one response was reduced, there was no bias toward either measure. In cats, the effects of intravitreal injection of various doses of kainic acid on the retina were evaluated electrophysiologically, and structural damage was assessed histologically. After 25 nmol of kainic acid, the pattern electroretinograms and oscillatory potentials were reduced but neither the b-waves nor the scotopic threshold responses, were affected. Histologic studies of retina
Who reads Selective Reduction of Oscillatory Potentials and Pattern Electroretinograms After Retinal Ganglion Cell Damage by Disease in Humans or by Kainic Acid Toxicity in Cats?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Vaegan; S. L. Graham; I. Goldberg; T. J. Millar
- Publisher
- Springer-Verlag; Kluwer Academic Publishers; Springer Science and Business Media LLC (ISSN 0012-4486)
- Published
- 1990
- Language
- EN
- Field
- Medicine (Health Sciences)
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