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The document discusses the development of a sensitive and specific method for quantifying agaritine, a genotoxic hydrazine found in mushrooms, using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The method demonstrated high recovery rates and precision for agaritine in mushroom and mouse plasma samples, indicating its potential for evaluating the risk of mushroom hydrazines to humans. The study highlights the importance of understanding the mutagenicity of agaritine and its metabolites in food

Author

Pienov

Language

EN